A new study has identified a mutation in the TREM2 gene that disrupts the brains ability to clear toxic amyloid plaques, increasing Alzheimers disease risk. The mutation, called T96K, keeps the TREM2 gene in an overactive state that paradoxically weakens microglial cleanup activity, especially in females.
A new study has identified a mutation in the TREM2 gene that disrupts the brains ability to clear toxic amyloid plaques, increasing Alzheimers disease risk. The mutation, called T96K, keeps the TREM2 gene in an overactive state that paradoxically weakens microglial cleanup activity, especially in females.
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